Well most of the roads North of Rt. 6 are motorcycle country, it's all rural. From Nicholson I would suggest going North to Hop Bottom, at hop bottom Hook a left onto 167, take that to Montrose. From Montrose take 29 North to Lawsville Center and make a left onto 4002, I forget the name of the road at the moment but you can't miss it, there's a sign for Laurel Lake there.
Go around the lake and hook up with 4004 on the other side. Again Can't miss it, If I remember correctly its the same road just different number. you take that to St. Joseph and take 267 South to Lawton. From Lawton you have choice... You can go either follow 267 back to Meshoppen which is near the property, 267 is nice road but the other options like 367 which comes out in Laceyville or 706 which goes to Wyalusing would be nicer. Guess it depends on your time constraints.
Overall that's probably a good 2-3 hour trip.
The other way which could involve an adventurous side trip on a dirt road is to head up over the mountain from Meshoppen to Rt. 87, not sure of the name of the road from Meshoppen but if you're going west on Rt. 6 from Tunkhannock and just want to see the majority of the route just get on 87 after Tunkhannock instead. Follow 87 to Dushore. Get on 487 South which will head you towards rickets Glenn State Park and Red Rock. This also goes through some of the coldest parts of Pennsylvania, specifically Lopez which has the coldest recorded temperature in PA.
On the top of the mountain before the main entrance to Ricketts Glen state park you come to interesting decision.
There is dirt road off a place where you can park to go hunting. It's not marked last I checked but it's about a mile or two from the entrance, the road itself the last time I was on it was pretty good but its been a while. That meanders across the top of the mountain for a few miles then hooks up with a old train track bed complete with old train bridges, note there is no railings on the bridges but they are quite small. There's planks to facilitate driving across them. There's also a dam where they used to cut ice which was one of the reasons for the railroad. Once you get around the dam area it starts to descend down the mountain. It's a good 10-15 mile ride on this road but the scenery is awesome. It follows a creek its entire length. That brings you out at Noxen on Rt. 29
The other choice is to go down the mountain from Rickets Glenn state park which is very steep decent but is a regular road. Make a left onto 118, there's place to pull over a few miles up the road which has hiking trails, there are numerous waterfalls along these trails and are quite popular. On 118 follow that and make left onto Mooretown road which will bring you to 29, head north on 29.
The dirt Road above comes out at Noxen which is also on 29. Follow 29 North towards Tunkhannock, on the left about 2 or 3 miles before Tunkhannock is road called Sugar Hollow, you can't miss it. As you're going up 29 you'll go down a pretty long hill then over a bridge. There's a rest stop on the left after the bridge then a long straight away. At the end of the straight a way you go up over a small rise then down and it's right there on the left.
Sugar Hollow is one the better roads I know, there are some farms on that road that are picture perfect. That will bring you back out on 87 not too far from where you started.
That too is probably a 3 hour ride.
I could lead you around in circles for days if you wanted. I know some of those roads better than the locals, especially if it's the best way to get from one place to another that is of any distance.
Here's picture from the dam, note the date.
That's yours truly on the left. I'm a glutton for punishment, my head felt like someone was in there with a jackhammer when that picture was taken.
